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China Wholesale Ketoconazole Factory
Wholesale Ketoconazole CAS:65277-42-1
Wholesale Ketoconazole Chemical Properties
MF:C26H28Cl2N4O4
MW:531.43
EINECS:265-667-4
Melting point:146°C
Boiling point :753.4±60.0 °c(predicted)
Density:1.4046 (rough estimate)
Refractive index:-10.5 ° (c=0.4, chcl3)
Fp :9℃
Solubilitymethanol: Soluble50mg/ml
Pka:Pka 3.25/6.22(h2o,t =25,i=0.025) (uncertain)
Optical activity:[α]20/D -1 to 1°, c = 4 in methanol
Water Solubility:Soluble in DMSO, ethanol, chloroform, water, and methanol.
Wholesale Ketoconazole CAS:65277-42-1 Introduction
H&Z® Wholesale Ketoconazole is a synthetic antifungal used to prevent and treat fungal skin infections, especially in immunocompromised patients such as those with AIDS or those on chemotherapy.
Wholesale Ketoconazole is sold commercially as an anti-dandruff shampoo, topical cream, and oral tablet
Wholesale Ketoconazole CAS:65277-42-1 Specification:
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Test
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Specifications
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Result
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Assay by HPLC
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98%
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99.27%
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|
Appearance
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Yellow fine powder
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Complies
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Odor & taste
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Slight bitter
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Complies
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Mesh size
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100% pass 80 mesh
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Complies
|
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Solubility
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Soluble in water
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Complies
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|
Loss on drying
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≤2.0%
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1.15%
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Heavy metals PPM
Microbiology
Total Plate Count
Yeast & Mold
E.Coli
S.Aureus
Salmonella
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<30ppm
<1000cfu/g
<100cfu/g
Negative
Negative
Negative
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Complies
800cfu/g
90cfu/g
Complies
Complies
Complies
|
Wholesale Ketoconazole CAS:65277-42-1 Function
Wholesale Ketoconazole is usually prescribed for fungal infections of the skin and mucous membranes, such as athlete's foot, ringworm, candidiasis (yeast infection or thrush), jock itch, and tinea versicolor.
Topical Wholesale Ketoconazole is also used as a treatment for dandruff (seborrheic dermatitis of the scalp) and for seborrheic dermatitis on other areas of the body, perhaps acting in these conditions by suppressing levels of the fungus Malassezia furfur on the skin.
Wholesale Ketoconazole CAS:65277-42-1 Application
1.Hair loss
Wholesale Ketoconazole shampoo in conjunction with an oral 5α-reductase inhibitor has been used off label to treat and rogenic alopecia.
The antifungal properties of Wholesale Ketoconazole reduce scalp microflora and consequently may reduce follicular inflammation that contributes to alopecia.Limited clinical studies suggest Wholesale Ketoconazole shampoo used either alone or in com-bination with other treatments may be useful in reducing hair loss. At least one study has been performed showing that Wholesale Ketoconazole may be useful in temporarily reducing erectile function in postoperative penile surgery patients.
2.Veterinary use
H&Z® Wholesale Ketoconazole is also sometimes prescribed by veterinarians for use on pets, often as unflavored that may need to be cut to smaller size for correct dosage.
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