Polyglutamic Acid
  • Polyglutamic AcidPolyglutamic Acid

Polyglutamic Acid

China H&Z® Polyglutamic acid is also known as natto gum and polyglutamic acid. It is a water-soluble, biodegradable, non-toxic, biopolymer prepared by microbial fermentation. Its moisturizing and water-locking effect is 500 times that of hyaluronic acid. Mainly used for moisturizing, whitening, antibacterial, and improving skin health.

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Product Description

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Polyglutamic Acid/Poly(L-glutamate) CAS:25513-46-6

Other Common Names:Natto Gum; PGA;γ-PGA;γ-Polyglutamic Acid;Gamma-Polyglutamic acid

Polyglutamic Acid/Poly(L-glutamate) Introduction:

H&Z® Polyglutamic Acid is a water soluble, biodegradable, non-toxic biopolymer produced by microbial fermentation.

Poly(L-glutamate)/PGA is a sticky material first found in“natto”, a fermented soybean.

Poly(L-glutamate)/PGA is an unusual anionic, naturally occurring homo polyamide that is made of D & L glutamic acid units connected by amide linkages between alpha amino & gamma carboxylic acid groups.

Gamma-poly-glutamic acid (gamma-PGA) is a natural occurring, multi-functional, and biodegradable biopolymer. It is produced through fermentation by Bacillus subtilis using glutamic acid. PGA is consists of glutamic acid monomers crosslinked betweenα-amino andγ-carboxyl groups, and the molecular weight of PGA is usually between 100~1000 kDa. It is water-soluble, edible and non-toxictowards human, and is environment friendly. It has broad applications in the fields of medicine, food, cosmetics, and water treatment.

Polyglutamic Acid/Poly(L-glutamate) Specification:


Molecular weight(Dalton)



Quite High Molecular Weight 




High Molecular Weight(New Type)



High Molecular Weight(Old Type)



Low Molecular Weight



Quite Low Molecular Weight



Low Molecular Weight

About 10000




Polyglutamic Acid/Poly(L-glutamate) Function:

1. Active component for lasting moisturizing and resistance to dry conditions of human skin.

2. Increasing the elasticity of human skin and keeping it tight and smooth.

3. Inhibiting the formation of melanin remarkably.

4. Keeping pH balance of human skin.

5. Forming a slow-release delivery system and therefore improving the absorption capacity of   nutrients in cosmetics.

6. Enhancing color fastness after hair dying.

Polyglutamic Acid/Poly(L-glutamate) Application:

1. Irrigation Fertilizer:

It can be added to compound fertilizer by rate of 5-8%, improve the nutrient content of compound fertilizer, increases crops’direct absorption.

2. Food Industry

As thickener for foods & drinks, improves taste of drinks, stabilizer in ice creams, texture enhancer, binder, animal feed supplement, antifreezing agent or cryoprotectant, bitterness relieving agent, as an additive in preparation of starch foods (bakery & noodles) for avoiding staling, enhancing food texture and maintaining food shapes.

3. Medical treatment

Drug release carrier, a haemostatic agent, soft tissue augmentation.

4. Cosmetics Ingredient

As a humectant, moisturizer to improve skin care quality, as a whitening agent, has anti wrinkle property which gives long lasting effect.

5.Water treatment

Heavy metal absorbent or chelating agent.Biopolymer flocculant, a substitute for polyacrylamide.

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