Albendazole
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Albendazole

Albendazole made by China H&Z® factory is an imidazole derivative broad-spectrum insect repellent medicine.It was discovered by glaxosmithkline's animal health laboratory in 1972.Albendazole has been included in the world health organization's list of essential medicines and is one of the most important basic health drugs.
Albendazole is an effective and low - toxic broad-spectrum insect repellent.Clinical use can be used to drive roundworm, pinworm, tapeworm, whipworm, hookworm, dung beetle, etc.In the body metabolism after class for sulfoxide or sulfone, inhibition of parasites on the absorption of glucose, lead to the insect body glycogen depletion, or inhibition of fumaric acid reductase system, prevent the generation of ATP, the parasite can survive and reproduce.

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Product Description

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China Albendazole Factory


Albendazole CAS:54965-21-8


Albendazole Chemical Properties

MF:C12H15N3O2S

MW:265.33

EINECS:259-414-7

Melting point:208-210°c

Density:1.2561 (rough estimate)

Refractive index:1.6740 (estimate)

Solubilitypractically insoluble in water, freely soluble in anhydrous formic acid, very slightly soluble in methylene chloride, practically insoluble in ethanol (96 per cent).

Pka:10.72±0.10(predicted)

Water Solubility:0.75mg/L(209ºC)


Albendazole CAS:54965-21-8 Specification:

Items

Specification

Appearance

White or almost white powder

Identification

Positive 

Loss on Drying

≤0.5%

Residue on Ignition

≤0.2%

Related Compounds

≤1.5%

Melting Point

206.0-212.0°C

Particle Size

≤20 Microns

Assay(on dried basis)

≥98.5%

Standard

CP2010


Items

Specification

Appearance

White or almost white powder

Identification

Positive 

Loss on Drying

≤0.5%

Residue on Ignition

≤0.2%

Related Compounds

≤0.5%

Particle Size

≤20 Microns

Assay(on dried basis)

98.0~102.0%

Standard

USP37


Albendazole CAS:54965-21-8 Introduction:

1. H&Z® Albendazole is a kind of broad spectrum thiabendazole class anthelmintics which can be applied by both human and animal.

2. Albendazole can inhibit the parasite growth and reproduction by inhibiting the intestinal and absorbing the intracellular protein, resulting in the failure of parasite in sugar uptake which is indispensable for their survival, thus causing the endogenous glycogen depletion of insects and further inhibiting fumarate reductase system, preventing the generation of adenosine triphosphate, causing that the parasites are not be able to further survive and reproduce, and ultimately die due to energy depletion.


Albendazole CAS:54965-21-8 Functions

H&Z® Albendazole is an anthelmintic or anti- worm medication. It prevents newly hatched insect larvae (worms) from growing or multiplying in your body.  

Albendazole is used to treat certain infections caused by worms such as pork tapeworm and dog tapeworm.

1. Albendazole is highly effective broad spectrum anthelmintic drugs, is benzimidazole deworming drugs in the broader spectrum.

2. Albendazole is highly active against nematodes, schistosomes, tapeworms, but also significantly inhibited the development of eggs.

3. Albendazole on parasitic nematodes in a variety of animals, schistosomes, tapeworms and cysticerci also has a significant role in repelling.

4. Albendazole is applied to get rid of roundworm, pinworm, hookworm, whipworm, can also be used for deworming livestock.


Albendazole CAS:54965-21-8 Application:

1. Broad spectrum antiparasitic; Used to expel nematode, tapeworms, trematode worms and ectoparasites in livestock.


2. Albendazole has a broad spectrum of insect repellents, and has a strong effect on nematode, tapeworm and trematode; Its mechanism of action is to bind to microtubulin in the worm and prevent it polymerize withα-tubulin to form microtubules, thus affecting cell reproduction processes such as mitosis, protein assembly and energy metabolism.


3. Ivermectin has a good effect on the internal and external parasites, especially arthropod insects and internal nematode worms; It is mainly used to expel the gastrointestinal nematodiasis, lungworm and ectoparasites; The mechanism of deworming is to promote the release of GABA by presynaptic neurons, thus opening GABA-mediated chloride ion channels; Chlorine ion flow can reduce the resistance of cell membrane, cause the slight depolarization of the postsynaptic membrane static potential, interfere with the signal transmission between the nerve muscles, and also cause the insect body to relax and paralyze, resulting in the death or expulsion of the insect body.




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