Amantadine HCl

Our well-equipped facilities and great excellent command throughout all stages of generation enables us to guarantee total customer fulfillment for Renewable Design for China Pharmaceutical Grade Amantadine Hydrochloride Powder CAS 665-66-7, The continual availability of significant grade merchandise in combination with our excellent pre- and after-sales support ensures strong competitiveness in an increasingly globalized market. Renewable Design for China Amantadine Hydrochloride, 1-Adamantanamine Hydrochloride, As an experienced factory we also accept customized order and make it same as your picture or sample specifying specification and customer design packing. The main goal of the company is to live a satisfactory memory to all the customers,and establish a long term win-win business relationship. For more information,remember to contact us H&Z®. And it's our great pleasure if you like to have a personally meeting in our office.

China Amantadine HCl Factory

Amantadine CAS 768-94-5

Amantadine Hydrochloride/Amantadine HCl CAS 665-66-7
Amantadine hcl CAS 665-66-7 Amantadine Hydrochloride 
Product Name 1-Adamantanamine hydrochloride
Molecular Formula C10H17N
Molecular Weight 151.2487
CAS Registry Number 665-66-7
Quality:CP/BP
Density 1.067g/cm3
Melting point 300°C
Boiling point 225.692°C at 760 mmHg
Refractive index 1.558
Flash point 95.974°C
Water solubility soluble
Vapour Pressur 0.085mmHg at 25°C

Amantadine HCl CAS 665-66-7 Specification:

tems	Specification
Appearance	White crystal or crystalline powder, odo(u)rless and bitter
Identification	Meets the requirements
Acidity	PH 3.0~5.5
Clarity and color	The solution should be clear and nearly colorless
Loss on drying	≤0.5%
Residue on ignition	≤0.1%
Heavy metals	≤0.001%
Related substances	Any individual impurity 0.3% Total impurity 1.0%
Assay	≥98.5%
Standard	USP39

Amantadine HCl CAS 665-66-7 Usage: 
H&Z® Amantadine HCI lis used as an intermediate in the synthesis of amantadanes.Used for the synthesis of adamantane derivatives and adalbalin.Reaction with vinyliden e chlorid e yields 1- amantadine acetic acid.

Amantadine HCl CAS 665-66-7 Function:
Amantadine Hydrochloride is the hydrochloride salt of amantadine, a synthetic tricyclic amine with antiviral, antiparkinsonian, and antihyperalgesic activities. Amantadine appears to exert its antiviral effect against the influenza A virus by interfering with the function of the transmembrane domain of the viral M2 protein, thereby preventing the release of infectious viral nucleic acids into host cells; furthermore, this agent prevents virus assembly during virus replication. Amantadine exerts its antiparkinsonian effects by stimulating the release of dopamine from striatal dopaminergic nerve terminals and inhibiting its pre-synaptic reuptake. This agent may also exert some anticholinergic effect through inhibition of N-methyl-D-aspartic acid (NMDA) receptor-mediated stimulation of acetylcholine, resulting in antihyperalgesia.
Amantadine hydrochloride is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also usedas an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in
movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.